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文献集次世代NOGマウス

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文献集 次世代NOGマウス



Predominant development of mature and functional human NK cells in a novel human IL-2-producing transgenic NOG mouse.
Katano I, Takahashi T, Ito R, Kamisako T, Mizusawa T, Ka Y, Ogura T, Suemizu H, Kawakami Y, Ito M.
J Immunol. 2015 Apr 1;194(7):3513-25.

Strain preservation of experimental animals: Vitrification of two-cell stage embryos for multiple mouse strains. Cryobiology.
Eto T, Takahashi R, Kamisako T.
Cryobiology. 2015 Apr;70(2):150-5.

Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo.
Yamada E, Yoshikawa R, Nakano Y, Misawa N, Koyanagi Y, Sato K
Viruses. 2015 Mar 23;7(3):1373-90.

Visualization of the human CD4+ T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/γc(null) (NOG) mice by retrogenic expression of the human TCR gene.
Takahashi T, Katano I, Ito R, Ito M.
Biochem Biophys Res Commun. 2015 Jan 2;456(1):219-24.

Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice.
Matsushita H, Yahata T, Sheng Y, Nakamura Y, Muguruma Y, Matsuzawa H, Tanaka M, Hayashi H, Sato T, Damdinsuren A, Onizuka M, Ito M, Miyachi H, Pandolfi PP, Ando K.
PLoS One. 2014 Nov 4;9(11)

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.
Sato K, Takeuchi JS, Misawa N, Izumi T, Kobayashi T, Kimura Y, Iwami S, Takaori-Kondo A, Hu WS, Aihara K, Ito M, An DS, Pathak VK, Koyanagi Y.
PLoS Pathog. 2014 Oct 16;10(10)

Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1.
Negishi N, Suzuki D, Ito R, Irie N, Matsuo K, Yahata T, Nagano K, Aoki K, Ohya K, Hozumi K, Ando K, Tamaoki N, Ito M, Habu S.
Exp Hematol. 2014 Jun;42(6):487-94.e1.

NOD-Rag2null IL-2Rγnull Mice: An Alternative to NOG Mice for Generation of Humanized Mice.
Ikumi Katano, Ryoji Ito, Tsutomu Kamisako, Tomoo Eto, Tomoyuki Ogura, Kenji Kawai, Hiroshi Suemizu, Takeshi Takahashi, Yutaka Kawakami, and Mamoru Ito
Exp Anim. 2014; 63(3): 321-330.

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells.
Hirose S, Takayama N, Nakamura S, Nagasawa K, Ochi K, Hirata S, Yamazaki S, Yamaguchi T, Otsu M, Sano S, Takahashi N, Sawaguchi A, Ito M, Kato T, Nakauchi H, Eto K.
Stem Cell Reports. 2013 Dec 5;1(6):499-508.

HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo.
Sato K, Misawa N, Iwami S, Satou Y, Matsuoka M, Ishizaka Y, Ito M, Aihara K, An DS, Koyanagi Y.
PLoS Pathog. 2013;9(12):e1003812.

Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice.
Ito R, Takahashi T, Katano I, Kawai K, Kamisako T, Ogura T, Ida-Tanaka M, Suemizu H, Nunomura S, Ra C, Mori A, Aiso S, Ito M.
J Immunol. 2013 Sep 15;191(6):2890-9.

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome.
Saida S, Watanabe K, Sato-Otsubo A, Terui K, Yoshida K, Okuno Y, Toki T, Wang R, Shiraishi Y, Miyano S, Kato I, Morishima T, Fujino H, Umeda K, Hiramatsu H, Adachi S, Ito E, Ogawa S, Ito M, Nakahata T, Heike T.
Blood. 2013 May 23;121(21):4377-87.

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.
Zhang Ya, Patel S, Abdelouahab H, Wittner M, Willekens C, Shen S, Betems A, Joulin V, Opolon P, Bawa O, Pasquier F, Ito M, Fujii N, Gonin P, Solary E, Vainchenker W, Coppo P, De Botton S, Louache F.
Cell Death Dis. 2012 Oct 4;3:e396.

Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rγnull mice is attributed to a lack of CD11c+B220+CD122+ cells.
Ito R, Katano I, Ida-Tanaka M, Kamisako T, Kawai K, Suemizu H, Aiso S, Ito M.
J Immunol. 2012 Nov 1;189(9):4313-20.

Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts.
Ito R, Negishi N, Irie N, Matsuo K, Suzuki D, Katano I, Hayakawa E, Kawai K, Kamisako T, Eto T, Ogura T, Hozumi K, Ando K, Aiso S, Tamaoki N, Habu S, Ito M.
Exp Hematol. 2012 Nov;40(11):953-963.

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.
Yahata T, Takanashi T, Muguruma Y, Ibrahim AA, Matsuzawa H, Uno T, Sheng Y, Onizuka M, Ito M, Kato S, Ando K.
Blood. 2011 Sep 15;118(11):2941-50.

Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice.
Sato K, Misawa N, Fukuhara M, Iwami S, An DS, Ito M, Koyanagi Y.
J Virol. 2012 May;86(9):5000-13.

Current advances in humanized mouse models.
Ito R, Takahashi T, Katano I, Ito M.
Cell Mol Immunol. 2012 May;9(3):208-14.

Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse.
Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K.
Int Immunol. 2012 Apr;24(4):243-52.

T-cell receptor gene therapy targeting melanoma-associated antigen-A4 inhibits human tumor growth in non-obese diabetic/SCID/γcnull mice.
Shirakura Y, Mizuno Y, Wang L, Imai N, Amaike C, Sato E, Ito M, Nukaya I, Mineno J, Takesako K, Ikeda H, Shiku H.
Cancer Sci. 2012 Jan;103(1):17-25.

Novel mouse xenograft models reveal a critical role of CD4+ T cells in the proliferation of EBV-infected T and NK cells.
Imadome K, Yajima M, Arai A, Nakazawa A, Kawano F, Ichikawa S, Shimizu N, Yamamoto N, Morio T, Ohga S, Nakamura H, Ito M, Miura O, Komano J, Fujiwara S.
PLoS Pathog. 2011 Oct;7(10):e1002326.

The mouse is out of the bag: insights and perspectives on HIV-1-infected humanized mouse models.
Sato K, Koyanagi Y.
Exp Biol Med (Maywood). 2011 Aug;236(8):977-85.

Mismatched human leukocyte antigen class II-restricted CD8+ cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation.
Hirosawa T, Torikai H, Yanagisawa M, Kamei M, Imahashi N, Demachi-Okamura A, Tanimoto M, Shiraishi K, Ito M, Miyamura K, Shibata K, Kikkawa F, Morishima Y, Takahashi T, Emi N, Kuzushima K, Akatsuka Y.
Cancer Sci. 2011 Jul;102(7):1281-6.

Epstein-Barr virus induces erosive arthritis in humanized mice.
Kuwana Y, Takei M, Yajima M, Imadome K, Inomata H, Shiozaki M, Ikumi N, Nozaki T, Shiraiwa H, Kitamura N, Takeuchi J, Sawada S, Yamamoto N, Shimizu N, Ito M, Fujiwara S.
PLoS One. 2011;6(10):e26630.

Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis
Kato I, Niwa A, Heike T, Fujino H, Saito MK, Umeda K, Hiramatsu H, Ito M, Morita M, Nishinaka Y, Adachi S, Ishikawa F, Nakahata T.
PLoS One. 2011;6(11):e27042.

A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice.
Sato K, Misawa N, Nie C, Satou Y, Iwakiri D, Matsuoka M, Takahashi R, Kuzushima K, Ito M, Takada K, Koyanagi Y.
Blood. 2011 May 26;117(21):5663-73.

Establishment of a xenograft model of human myelodysplastic syndromes.
Muguruma Y, Matsushita H, Yahata T, Yumino S, Tanaka Y, Miyachi H, Ogawa Y, Kawada H, Ito M, Ando K.
Haematologica. 2011 Apr;96(4):543-51.

The reconstituted 'humanized liver' in TK-NOG mice is mature and functional.
Hasegawa M, Kawai K, Mitsui T, Taniguchi K, Monnai M, Wakui M, Ito M, Suematsu M, Peltz G, Nakamura M, Suemizu H.
Biochem Biophys Res Commun. 2011 Feb 18;405(3):405-10.

Immunodeficient NOD-scid IL-2Rγ(null) mice do not display T and B cell leakiness.
Katano I, Ito R, Eto T, Aiso S, Ito M.
Exp Anim. 2011;60(2):181-6.

In vivo assay of human NK-dependent ADCC using NOD/SCID/gammac(null) (NOG) mice.
Shiokawa M, Takahashi T, Murakami A, Kita S, Ito M, Sugamura K, Ishii N.
Biochem Biophys Res Commun. 2010 Sep 3;399(4):733-7.

Remarkable lethal G-to-A mutations in vif-proficient HIV-1 provirus by individual APOBEC3 proteins in humanized mice.
Sato K, Izumi T, Misawa N, Kobayashi T, Yamashita Y, Ohmichi M, Ito M, Takaori-Kondo A, Koyanagi Y.
J Virol. 2010 Sep;84(18):9546-56.

Stem cell-like properties of the endometrial side population: implication in endometrial regeneration.
Masuda H, Matsuzaki Y, Hiratsu E, Ono M, Nagashima T, Kajitani T, Arase T, Oda H, Uchida H, Asada H, Ito M, Yoshimura Y, Maruyama T, Okano H.
PLoS One. 2010 Apr 28;5(4):e10387.

Dynamics of memory and naive CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1.
Sato K, Nie C, Misawa N, Tanaka Y, Ito M, Koyanagi Y.
Vaccine. 2010 May 26;28 Suppl 2:B32-7.

平成22年度


1. Tsuiji, K., T. Takeda, B. Li, A. Kondo, M. Ito, and N. Yaegashi. 2010. Establishment of a novel xenograft model for human uterine leiomyoma in immunodeficient mice. Tohoku J Exp Med 222:55-61.

2. Shiokawa, M., T. Takahashi, A. Murakami, S. Kita, M. Ito, K. Sugamura, and N. Ishii. 2010. In vivo assay of human NK-dependent ADCC using NOD/SCID/gammac(null) (NOG) mice. Biochem Biophys Res Commun 399:733-737.

3. Sato, K., C. Nie, N. Misawa, Y. Tanaka, M. Ito, and Y. Koyanagi. 2010. Dynamics of memory and naive CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1. Vaccine 28 Suppl 2:B32-37.

4. Sato, K., T. Izumi, N. Misawa, T. Kobayashi, Y. Yamashita, M. Ohmichi, M. Ito, A. Takaori-Kondo, and Y. Koyanagi. 2010. Remarkable Lethal G-to-A Mutations in vif-Proficient HIV-1 Provirus by Individual APOBEC3 Proteins in Humanized Mice. J Virol 84:9546-9556.

5. Masuda, H., Y. Matsuzaki, E. Hiratsu, M. Ono, T. Nagashima, T. Kajitani, T. Arase, H. Oda, H. Uchida, H. Asada, M. Ito, Y. Yoshimura, T. Maruyama, and H. Okano. 2010. Stem cell-like properties of the endometrial side population: implication in endometrial regeneration. PLoS One 5:e10387.

6. 伊藤守 ヒト化マウスの現状 細胞工学 29:238-242. (2010)

7. 佐藤 佳、小柳義夫HIV-1 のウイルス-宿主相互作用と新規治療薬の開発. 実験医学 28:2961-2968. (2010)