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References for NOG mouse

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References for NOG mouse



2012年

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2009年

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2006年

2005年

2004年

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2002年

2001年

2012年


1.Assessment of Benzene-Induced Hematotoxicity Using a Human-Like Hematopoietic Lineage in NOD/Shi-scid/IL-2Rγ(null) Mice.
Takahashi M, Tsujimura N, Yoshino T, Hosokawa M, Otsuka K, Matsunaga T, Nakasono S. PLoS One. 2012;7(12):e50448. Epub 2012 Dec 3.

2.A new in vivo model to analyze hepatic metastasis of the human colon cancer cell line HCT116 in NOD/Shi-scid/IL-2Rγnull (NOG) mice by 18F-FDG PET/CT.
Kawai K, Tamura K, Sakata I, Ishida J, Nagata M, Tsukada H, Suemizu H, Nakamura M, Abe Y, Chijiwa T. Oncol Rep. 2012 Nov 15. [Epub ahead of print] Exp. Anim. 60(2), 181-186, 2011

3.Stevens-Johnson syndrome/toxic epidermal necrolysis mouse model generated by using PBMCs and the skin of patients.
Saito N, Yoshioka N, Abe R, Qiao H, Fujita Y, Hoshina D, Suto A, Kase S, Kitaichi N, Ozaki M, Shimizu H. J Allergy Clin Immunol. 2012 Oct 27. [Epub ahead of print]

4.Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells.
Shimizu K, Mizuno T, Shinga J, Asakura M, Kakimi K, Ishii Y, Masuda K, Maeda T, Sugahara H, Sato Y, Matsushita H, Nishida K, Hanada KI, Dorrie J, Schaft N, Bickham K, Koike H, Ando T, Nagai R, Fujii SI. Cancer Res. 2012 Oct 29. [Epub ahead of print]

5. LGR5-Positive Colon Cancer Stem Cells Interconvert with Drug-Resistant LGR5-Negative cells and are Capable of Tumor Reconstitution.
Kobayashi S, Yamada-Okabe H, Suzuki M, Natori O, Kato A, Matsubara K, Jau Chen Y, Yamazaki M, Funahashi S, Yoshida K, Hashimoto E, Watanabe Y, Mutoh H, Ashihara M, Kato C, Watanabe T, Yoshikubo T, Tamaoki N, Ochiya T, Kuroda M, Levine AJ, Yamazaki T. Stem Cells. 2012 Dec;30(12):2631-44

6.Impact of the Integrin Signaling Adaptor Protein NEDD9 on Prognosis and Metastatic Behavior of Human Lung Cancer.
Kondo S, Iwata S, Yamada T, Inoue Y, Ichihara H, Kichikawa Y, Katayose T, Souta-Kuribara A, Yamazaki H, Hosono O, Kawasaki H, Tanaka H, Hayashi Y, Sakamoto M, Kamiya K, Dang NH, Morimoto C. Clin Cancer Res. 2012 Nov 15;18(22):6326-6338. Epub 2012 Oct 4.

7.Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice.
Wang C, Nakamura S, Oshima M, Mochizuki-Kashio M, Nakajima-Takagi Y, Osawa M, Kusunoki Y, Kyoizumi S, Imai K, Nakachi K, Iwama A. Int J Radiat Biol. 2012 Oct 25. [Epub ahead of print]

8.Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rgnull mice is attributed to a lack of CD11c+B220+CD122+ cells.
Ito R, Katano I, Ida M, Kamisako T, Kawai K, Suemizu H, Aiso S, Ito M J Immunol. 2012 Nov 1;189(9):4313-20

9.Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model.
Mori F, Ishida T, Ito A, Sato F, Masaki A, Takino H, Ri M, Kusumoto S, Komatsu H, Ueda R, Inagaki H, Iida S. Blood Cancer J. 2012 Apr;2(4):e67. Epub 2012 Apr 20.

10.POsteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts.
Ito R, Negishi N, Irie N, Matsuo K, Suzuki D, Katano I, Hayakawa E, Kawai K, Kamisako T, Eto T, Ogura T, Hozumi K, Ando K, Aiso S, Tamaoki N, Habu S, Ito M. Exp Hematol. 2012 Nov;40(11):953-963

11.Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice.
Moriya K, Suzuki M, Watanabe Y, Takahashi T, Aoki Y, Uchiyama T, Kumaki S, Sasahara Y, Minegishi M, Kure S, Tsuchiya S, Sugamura K, Ishii N. PLoS One. 2012;7(6):e37892. Epub 2012 Jun 20.

12.Humanized mice recapitulate key features of HIV-1 infection: a novel concept using long-acting anti-retroviral drugs for treating HIV-1.
Nischang M, Sutmuller R, Gers-Huber G, Audige A, Li D, Rochat MA, Baenziger S, Hofer U, Schlaepfer E, Regenass S, Amssoms K, Stoops B, Van Cauwenberge A, Boden D, Kraus G, Speck RF. PLoS One. 2012;7(6):e38853. Epub 2012 Jun 13.

13.["Humanized mice" produced by using immunodeficient NOG mice].
Suemizu H. Nihon Yakurigaku Zasshi. 2012 May;139(5):203-6. Japanese.

14.Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system.
Shima K, Mizuma M, Hayashi H, Nakagawa K, Okada T, Sakata N, Omura N, Kitamura Y, Motoi F, Rikiyama T, Katayose Y, Egawa S, Ishii N, Horii A, Unno M. J Exp Clin Cancer Res. 2012 Jun 6;31(1):55. [Epub ahead of print]

15.PCurrent advances in humanized mouse models.
Ito R, Takahashi T, Katano I, Ito M. Cell Mol Immunol. 2012 May;9(3):208-14.

16.Comprehensive evaluation of leukocyte lineage derived from human hematopoietic cells in humanized mice.
Takahashi M, Tsujimura N, Otsuka K, Yoshino T, Mori T, Matsunaga T, Nakasono S. J Biosci Bioeng. 2012 Apr;113(4):529-35.

17.Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system.
Shima K, Mizuma M, Hayashi H, Nakagawa K, Okada T, Sakata N, Omura N, Kitamura Y, Motoi F, Rikiyama T, Katayose Y, Egawa S, Ishii N, Horii A, Unno M. J Exp Clin Cancer Res. 2012 Jun 6;31:55.

18.Multiple myeloma-related deregulation of bone marrow-derived CD34(+) hematopoietic stem and progenitor cells.
Bruns I, Cadeddu RP, Brueckmann I, Frobel J, Geyh S, Bust S, Fischer JC, Roels F, Wilk CM, Schildberg FA, Hunerliturkoglu AN, Zilkens C, Jager M, Steidl U, Zohren F, Fenk R, Kobbe G, Brors B, Czibere A, Schroeder T, Trumpp A, Haas R Blood. 2012 Sep 27;120(13):2620-30.

19.Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse.
Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K. Int Immunol. 2012 Apr;24(4):243-52.

20.Neovascular niche for human myeloma cells in immunodeficient mouse bone.
Iriuchishima H, Takubo K, Miyakawa Y, Nakamura-Ishizu A, Miyauchi Y, Fujita N, Miyamoto K, Miyamoto T, Ikeda E, Kizaki M, Nojima Y, Suda T. PLoS One. 2012;7(2):e30557. Epub 2012 Feb 7.

21.In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.
Yamazaki H, Suemizu H, Shimizu M, Igaya S, Shibata N, Nakamura M, Chowdhury G, Guengerich FP. Chem Res Toxicol. 2012 Feb 20;25(2):274-6.

22.T-cell receptor gene therapy targeting melanoma-associated antigen-A4 inhibits human tumor growth in non-obese diabetic/SCID/γcnull mice.
Shirakura Y, Mizuno Y, Wang L, Imai N, Amaike C, Sato E, Ito M, Nukaya I, Mineno J, Takesako K, Ikeda H, Shiku H. Cancer Sci. 2012 Jan;103(1):17-25.

2011年


1.The cytostatic effects of lovastatin on ACC-MESO-1 cells.
Asakura K, Izumi Y, Yamamoto M, Yamauchi Y, Kawai K, Serizawa A, Mizushima T, Ohmura M, Kawamura M, Wakui M, Adachi T, Nakamura M, Suematsu M, Nomori H. J Surg Res. 2011 Oct;170(2):e197-209.

2.Epstein-Barr virus induces erosive arthritis in humanized mice.
Kuwana Y, Takei M, Yajima M, Imadome K, Inomata H, Shiozaki M, Ikumi N, Nozaki T, Shiraiwa H, Kitamura N, Takeuchi J, Sawada S, Yamamoto N, Shimizu N, Ito M, Fujiwara S. PLoS One. 2011;6(10):e26630.

3.Mismatched human leukocyte antigen class II-restricted CD8 cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation.
Hirosawa T, Torikai H, Yanagisawa M, Kamei M, Imahashi N, Demachi-Okamura A, Tanimoto M, Shiraishi K, Ito M, Miyamura K, Shibata K, Kikkawa F, Morishima Y, Takahashi T, Emi N, Kuzushima K, Akatsuka Y. Cancer Sci. 2011 Jul;102(7):1281-6.

4.Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice.
Kubo A, Ohmura M, Wakui M, Harada T, Kajihara S, Ogawa K, Suemizu H, Nakamura M, Setou M, Suematsu M. Anal Bioanal Chem. 2011 Jun;400(7):1895-904

5.The effect of human fetal liver-derived mesenchymal stem cells on CD34+ hematopoietic stem cell repopulation in NOD/Shi-scid/IL-2Rg(null) mice.
Yang HM, Cho MR, Sung JH, Yang SJ, Nam MH, Roh CR, Kim JM, Shin M, Song SH, Kwon CH, Joh JW, Kim SJ. Transplant Proc. 2011 Jun;43(5):2004-8.

6.The Reconstituted 'Humanized Liver' in TK-NOG Mice is Mature and Functional
Hasegawa M, Kawai K, Mitsui T, Taniguchi K, Monnai M, Wakui M, Ito M, Suematsu M, Peltz G, Nakamura M, Suemizu H Biochem Biophys Res Commun. 2011 Jan 13

7.Immunodeficient NOD-scid IL-2Rgnull Mice Do Not Display T and B cell Leakness
Katano I, Ito R, Eto T, Aiso S, Ito M Exp. Anim. 60(2), 181-186, 2011

8.「ヒト化マウスの現状と将来展望」
伊藤守 MDS (Medical Science Digest) vol. 37, 44-45

9. Establishment of a xenograft model of human myelodysplastic syndromes
Muguruma, Y., H. Matsushita, T. Yahata, S. Yumino, Y. Tanaka, H. Miyachi, Y. Ogawa, H. Kawada, M. Ito, and K. Ando Haemato logica 96:543-551 2011

10. Mismatched HLA class II-restricted CD8(+) cytotoxic T-cells may serve selective GVL effects following allogeneic hematopoietic cell transplantation
Hirosawa, T., H. Torikai, M. Yanagisawa, M. Kamei, N. Imahashi, A. Demachi-Okamura, M. Tanimoto, K. Shiraishi, M. Ito, K. Miyamura, K. Shibata, F. Kikkawa, Y. Morishima, T. Takahashi, N. Emi, K. Kuzushima, and Y. Akatsuka Cancer Sci Apr 5 2011

2010年


1.Multiple integrations of human T-lymphotropic virus type 1 proviruses in the engrafted cells from the asymptomatic carriers in NOD/SCID/gammacnull mice
Yamamoto I, Takajo I, Umeki K, Morishita K, Hatakeyama K, Kataoka H, Nomura H, Okayama A Intervirology. 2010;53(4):229-39

2.Establishment of long-term model throughout regular menstrual cycles in immunodeficient mice
Kikuchi-Arai M, Murakami T, Utsunomiya H, Akahira J, Suzuki-Kakisaka H, Terada Y, Tachibana M, Hayasaka S, Ugajin T, Yaegashi N Am J Reprod Immunol. 2010 Nov;64(5):324-32

3.Development of humanized models using NOG mice
Wakui M, Suemizu H Seikagaku. 2010 Apr;82(4):314-8. Japanese

4.Dynamics of memory and nalve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1
Sato K, Nie C, Misawa N, Tanaka Y, Ito M, Koyanagi Y Vaccine. 2010 May 26;28 Suppl 2:B32-7

5.In vivo assay of human NK-dependent ADCC using NOD/SCID/gammac(null) (NOG) mice
Shiokawa M, Takahashi T, Murakami A, Kita S, Ito M, Sugamura K, Ishii N Biochem Biophys Res Commun. 2010 Sep 3;399(4):733-7

6.Characterization of the epithelial cell adhesion molecule (EpCAM)+ cell population in hepatocellular carcinoma cell lines
Kimura O, Takahashi T, Ishii N, Inoue Y, Ueno Y, Kogure T, Fukushima K, Shiina M, Yamagiwa Y, Kondo Y, Inoue J, Kakazu E, Iwasaki T, Kawagishi N, Shimosegawa T, Sugamura K Cancer Sci. 2010 Oct;101(10):2145-55

7.Establishment of a novel xenograft model for human uterine leiomyoma in immunodeficient mice
Tsuiji K, Takeda T, Li B, Kondo A, Ito M, Yaegashi N Tohoku J Exp Med. 2010;222(1):55-61

8.「ヒト化マウスの現状」
伊藤守 細胞工学 29, 238-242, 2010

2009年


1.Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice
Shima H, Takubo K, Iwasaki H, Yoshihara H, Gomei Y, Hosokawa K, Arai F, Takahashi T, Suda T Biochem Biophys Res Commun. 2009 Jan 16;378(3):467-72

2.Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model
Ito A, Ishida T, Yano H, Inagaki A, Suzuki S, Sato F, Takino H, Mori F, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R Cancer Immunol Immunother. 2009 Aug;58(8):1195-206

3.In vivo efficacy of anti-MPL agonist antibody in promoting primary human hematopoietic cells
Kai M, Hagiwara T, Emuta C, Chisaka Y, Tsuruhata K, Endo C, Inagaki Y, Miyazaki H, Kataoka S Blood. 2009 Mar 5;113(10):2213-6

4.Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/gammaCnull (NOG) mice
Chijiwa T, Abe Y, Ikoma N, Yamazaki H, Tsukamoto H, Suemizu H, Kawai K, Wakui M, Nishime C, Matsumoto H, Matsuyama M, Mukai M, Ueyama Y, Nakamura M Int J Oncol. 2009 Jan;34(1):5-13

5.Ectopic porcine spermatogenesis in murine subcutis: tissue grafting versus cell-injection methods
Watanabe T, Hayashi H, Kita K, Kubota Y, Ogawa T Asian J Androl. 2009 May;11(3):317-23

6.Variation in the incidence of teratomas after the transplantation of nonhuman primate ES cells into immunodeficient mice
Kishi Y, Tanaka Y, Shibata H, Nakamura S, Takeuchi K, Masuda S, Ikeda T, Muramatsu S, Hanazono Y Cell Transplant. 2008;17(9):1095-102

7.Effects of liposome-encapsulated hemoglobin on human immune system: evaluation in immunodeficient mice reconstituted with human cord blood stem cells
Kawaguchi AT, Kametani Y, Kato S, Furuya H, Tamaoki K, Habu S Artif Organs. 2009 Feb;33(2):169-76

8.Higher susceptibility of NOG mice to xenotransplanted tumors
Machida K, Suemizu H, Kawai K, Ishikawa T, Sawada R, Ohnishi Y, Tsuchiya T J Toxicol Sci. 2009 Feb;34(1):123-7

9.Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
Ito R, Katano I, Kawai K, Hirata H, Ogura T, Kamisako T, Eto T, Ito M Transplantation. 2009 Jun 15;87(11):1654-8

10.Spontaneous thymic lymphomas in the non-obese diabetic/Shi-scid, IL-2R gamma (null) mouse
Kato C, Fujii E, Chen YJ, Endaya BB, Matsubara K, Suzuki M, Ohnishi Y, Tamaoki N Lab Anim. 2009 Oct;43(4):402-4

11.The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice)
Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K Int Immunol. 2009 Jul;21(7):843-58

12.ERas is expressed in primate embryonic stem cells but not related to tumorigenesis
Tanaka Y, Ikeda T, Kishi Y, Masuda S, Shibata H, Takeuchi K, Komura M, Iwanaka T, Muramatsu S, Kondo Y, Takahashi K, Yamanaka S, Hanazono Y Cell Transplant. 2009;18(4):381-9

13.An in vivo model of priming of antigen-specific human CTL by Mo-DC in NOD/Shi-scid IL2rgamma(null) (NOG) mice
Inoue M, Senju S, Hirata S, Irie A, Baba H, Nishimura Y Immunol Lett. 2009 Sep 22;126(1-2):67-72

14.Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo
Ito A, Ishida T, Utsunomiya A, Sato F, Mori F, Yano H, Inagaki A, Suzuki S, Takino H, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R J Immunol. 2009 Oct 1;183(7):4782-91

15.T cell-mediated control of Epstein-Barr virus infection in humanized mice
Yajima M, Imadome K, Nakagawa A, Watanabe S, Terashima K, Nakamura H, Ito M, Shimizu N, Yamamoto N, Fujiwara S J Infect Dis. 2009 Nov 15;200(10):1611-5

16.「NOGマウスとヒト化マウス」
伊藤守 ファルマシア 45, 1077-1081, 2009

2008年


1.Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rgammanull (NOG) mice
Hamada K, Monnai M, Kawai K, Nishime C, Kito C, Miyazaki N, Ohnishi Y, Nakamura M, Suemizu H J Oncol., 32:153-159., 2008

2.Interleukin-4-Transgenic hu-PBL-SCID Mice: A Model for the Screening of Antiviral Drugs and Immunotherapeutic Agents against X4 HIV-1 Viruses
Okuma K, Tanaka R, Ogura T, Ito M, Kumakura S, Yanaka M, Nishizawa M, Sugiura W, Yamamoto N, Tanaka Y J Infect Dis197:134-141

3.Inhibition of IkappaB kinase beta restrains oncogenic proliferation of pancreatic cancer cells
Ochiai T, Saito Y, Saitoh T, Dewan MZ, Shioya A, Kobayashi M, Kawachi H, Muto S, Itai A, Uota S, Eishi Y, Yamamoto N, Tanaka S, Arii S, Yamaoka S J Med Dent Sci. 2008 Mar;55(1):49-59

4.Basic concept of development and practical application of animal models for human diseases
Nomura T, Tamaoki N, Takakura A, Suemizu H Curr Top Microbiol Immunol. 2008;324:1-24

5.NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models
Ito M, Kobayashi K, Nakahata T Curr Top Microbiol Immunol. 2008;324:53-76

6.Antigen-specific antibody production of human B cells in NOG mice reconstituted with the human immune system
Ito R, Shiina M, Saito Y, Tokuda Y, Kametani Y, Habu S Curr Top Microbiol Immunol. 2008;324:95-107

7.Humanized mice for human retrovirus infection
Koyanagi Y, Tanaka Y, Ito M, Yamamoto N Curr Top Microbiol Immunol. 2008;324:133-48

8.Novel metastasis models of human cancer in NOG mice
Nakamura M, Suemizu H Curr Top Microbiol Immunol. 2008;324:167-77

9.Humanizing bone marrow in immune-deficient mice
Ando K, Muguruma Y, Yahata T Curr Top Microbiol Immunol. 2008;324:77-86

10.Interferon-alpha 2b-induced thrombocytopenia is caused by inhibition of platelet production but not proliferation and endomitosis in human megakaryocytes
Yamane A, Nakamura T, Suzuki H, Ito M, Ohnishi Y, Ikeda Y, Miyakawa Y Blood. 2008 Aug 1;112(3):542-50

11.A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses
Yajima M, Imadome K, Nakagawa A, Watanabe S, Terashima K, Nakamura H, Ito M, Shimizu N, Honda M, Yamamoto N, Fujiwara S J Infect Dis. 2008 Sep 1;198(5):673-82

12.The effect of a novel, small non-peptidyl molecule butyzamide on human thrombopoietin receptor and megakaryopoiesis
Nogami W, Yoshida H, Koizumi K, Yamada H, Abe K, Arimura A, Yamane N, Takahashi K, Yamane A, Oda A, Tanaka Y, Takemoto H, Ohnishi Y, Ikeda Y, Miyakawa Y Haematologica. 2008 Oct;93(10):1495-504

13.Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice
Suemizu H, Hasegawa M, Kawai K, Taniguchi K, Monnai M, Wakui M, Suematsu M, Ito M, Peltz G, Nakamura M Biochem Biophys Res Commun. 2008 Dec 5;377(1):248-52

14.Establishing EGFP congenic mice in a NOD/Shi-scid IL2Rg(null) (NOG) genetic background using a marker-assisted selection protocol (MASP)
Suemizu H, Yagihashi C, Mizushima T, Ogura T, Etoh T, Kawai K, Ito M Exp Anim. 2008 Oct;57(5):471-7

15.Development of human Graafian follicles following transplantation of human ovarian tissue into NOD/SCID/gammac null mice
Terada Y, Terunuma-Sato Y, Kakoi-Yoshimoto T, Hasegawa H, Ugajin T, Koyanagi Y, Ito M, Murakami T, Sasano H, Yaegashi N, Okamura K Am J Reprod Immunol. 2008 Dec;60(6):534-40

2007年


1.Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses
Watanabe S, Terashima K, Ohta S, Horibata S, Yajima M, Shiozawa Y, Dewan MZ, Yu Z, Ito M, Morio T, Shimizu N, Honda M, Yamamoto N Blood, 109:212-218.,2007

2.Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice
Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T Leukemia, 21:136-142., 2007

3.Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel new quantitative model of metastasis in NOD/SCID/gcnull (NOG) mice
Suemizu H, Monnai M, Ohnishi Y, Ito M, Tamaoki N, Nakamura M International J Oncology, Oct;31(4):741-51.,2007

4.IkappaBalpha independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells
Watanabe M, Dewan MZ, Taira M, Shoda M, Honda M, Sata T, Higashihara M, Kadin ME, Watanabe T, Yamamoto N, Umezawa K, Horie R Lab Invest, 87:372-382., 2007

5.Humanized NOD/SCID/IL2R{gamma}null Mice Transplanted with Hematopoietic Stem Cells under non-Myeloablative Condition Show Analysis of HIV-1 Pathogenesis
Watanabe S, Ohta S, Yajima M, Terashima K, Ito M, Mugishima H, Fujiwara S, Shimizu K, Honda M, Shimizu N, Yamamoto N J Virol, 13259-13264., 2007

6.Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/gamma c(null) immunodeficient mice
Masuda H, Maruyama T, Hiratsu E, Yamane J, Iwanami A, Nagashima T, Ono M, Miyoshi H, Okano HJ, Ito M, Tamaoki N, Nomura T, Okano H, Matsuzaki Y, Yoshimura Y Proc Natl Acad Sci U S A., 104:1925-1930., 2007

7.Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells
Ono, M, Maruyama T, Masuda H, Kajitani T, Nagashima T, Arase T, Ito M, Ohta K, Uchida H, Asada H, Yoshimura Y, Okano H, Matsuzaki Y Proc Natl Acad Sci U S A., 104., 2007

8.Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion
Fujino H, Hiramatsu H, Tsuchiya A, Niwa A, Noma H, Shiota M, Umeda K, Yoshimoto M, Ito M, Heike T, Nakahata T Faseb, J, 21:3499-3510., 2007

9.Angiopoietin-1 supports induction of hematopoietic activity in human CD34- bone marrow cells
Nakamura Y, Yahata T, Muguruma Y, Uno T, Sato T, Matsuzawa H, Kato S, Shirasugi Y, Hotta T, Ando K Exp Hematol. 2007 Dec;35(12):1872-83

2006年


1.Identification of human neutrophils during experimentally induced inflammation in mice with transplanted CD34+ cells from human umbilical cord blood
Doshi, M., M. Koyanagi, M. Nakahara, K. Saeki, K. Saeki, and A. Yuo Int J Hematol 84:231-237.,2006

2.A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis
Takanori Nakamura, Yoshitaka Miyakawa, Atsushi Miyamura, Akiko Yamane, Hidenori Suzuki, Mamoru Ito, Yasuyuki Ohnishi, Norihisa Ishiwata, Yasuo Ikeda, Nobutomo Tsuruzoe Blood, 107(11):4300-4307, 2006

3.Clonal analysis of thymus-repopulating cells presents direct evidence for self-renewal division of human hematopoietic stem cells
Yahata T, Yumino S, Seng Y, Miyatake H, Uno T, Muguruma Y, Ito M, Miyoshi H, Kato S, Hotta T, Ando K Blood, 108:2446-2454.,2006

4.Development of human-human hybridoma from anti-Her-2 peptide-producing B cells in immunized NOG mouse
Kametani Y, Shiina M, Katano I, Ito R, Ando K, Toyama K, Tsukamoto H, Matsumura T, Saito Y, Ishikawa D, Taki T, Ito M, Imai K, Tokuda Y, Kato S,Tamaoki N, Habu S Exp Hematol, 34:1239-1247, 2006

5.Efficient intervention of growth and infiltration of primary adult T-cell leukemia cell by an HIV protease inhibitor, ritonavir
M.Zahidunnabi Dewan, Jun-nosuke Uchihara, Kazuo Terashima, Mitsuo Honda, Tetsutaro Sata, Mamoru Ito, Nobutaka Fujii, Kimiharu Uozumi, Kunihiro Tsukasaki, Masao Tomonaga, Yoko Kubuki, Akihiko Okayama, Masakazu Toi, Naoki Mori, Naoki Yamamoto Blood,107(2):716-724, 2006

6.Establishment of a myeloid leukemia cell line, TRL-01, with MLL-ENL fusion gene
Manabu Ninomiya, Akihiro Abe, Toshiy Yokozawa, Kazutaka Ozeki, Kazuhito Yamamoto, Mamoru Ito, Masafumi Ito, Hitoshi Kiyoi, Nobuhiro Emi, Tomoki Naoe Cancer Genetics Cytogenetics,169:1-11,2006

7.Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment
Muguruma Y, Yahata T, Miyatake H, Sato T, Uno T, Itoh J, Kato S, Ito M, Hotta T, Ando K Blood, 107:1878-1887., 2006

8.Potential role of natural killer cells in controlling growth and infiltration of AIDS-associated primary effusion lymphoma cells
Dewan MZ, Terunuma H, Toi M, Tanaka Y, Katano H, Deng X, Abe H, Nakasone T, Mori N, Sata T, Yamamoto N Cancer Sci, 97:1381-1387.,2006

9.Role of natural killer cells in hormone-independent rapid tumor formation and spontaneous metastasis of breast cancer cells in vivo
Dewan MZ, Terunuma H, Takada M, Tanaka Y, Abe H, Sata T, Toi M, Yamamoto N Breast Cancer Res Treat, 2006

2005年


1.S100A4 Expression with Reduced E-cadherin Expression Predicts Distant Metastasis of Human Malignant Melanoma Cell Lines in the NOD/SCID/γcnull (NOG) Mouse Model
Norihiro Ikoma, Hitoshi Yamazaki, Yoshiyuki Abe, Yasuhisa Oida, Yasuyuki Ohnishi, Hiroshi Suemizu, Hozumi Matsumoto, Takashi Matsuyama, Yukinori Ohta, Akira Ozawa, Yoshito Ueyama, Masato Nakamura Oncology Reports, 14:633-637,2005

2.Hodgkin's Lymphoma Cells are Efficiently Engrafted and Tumor Marker CD30 is Expressed with Constitutive Nuclear Factor-кB Activity in Unconditioned NOD/SCID/γcnull Mice
Md.Zahidunnabi Dewan, Mariko Watanabe, Sunjida Ahmed, Kazuo Terashima, Sankichi Horiuchi, Tetsutaro Sata, Mitsuo Honda, Mamoru Ito, Toshiki Watanabe, Ryouichi Horie, Naoki Yamamoto Cancer Sci., 96(8):466-473,2005

3.Potent Anti-R5 Human Immunodeficiency Virus Type 1 Effects of a CCR5 Antagonist, AK602/ONO4128/GW873140, in a Novel Human Peripheral Blood Mononuclear Cell Nonobese Diabetic-SCID, Interleukin-2 Receptor
Hirotomo Nakata, Kenji Maeda, Toshikazu Miyakawa, Shiro Shibuyama, Masayoshi Matsuo, Yoshikazu Takaoka, Mamoru Ito, Yoshio Koyanagi, Hiroaki Mitsuya J. Virology, 79(4):2087-2096,2005

4.Natural killer cells in breast cancer cell growth and metastasisin SCID mice
Dewan MZ, Terunuma H, Ahmed S, Ohba K, Takada M, Tanaka Y, Toi M, Yamamoto N Biomed Pharmacother, 59 Suppl 2:S375-379.,2005

5.Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice
Matsuura-Sawada R, Murakami T, Ozawa Y, Nabeshima H, Akahira J, SatoY, Koyanagi Y, Ito M, Terada Y, Okamura K Hum Reprod,20:1477-1484.,2005

2004年


1.Competitive Repopulation Assay of Two Gene-Marked Cord Blood Units in NOD/SCID/γcnull Mice
Takashi Yahata, Kiyoshi Ando, Hiroko Miyatake, Tomoko Uno, Tadayuki Sato, Mamoru Ito, Shunichi Kato, Tomomitsu Hotta Molecular Therapy, 10(5),2004

2.Establishment of a New Model of Human Multiple Myeloma Using NOD/SCID/γcnull (NOG) Mice
Yoshitaka Miyakawa, Yasuyuki Ohnishi, Masashi Tomisawa, Makoto Monnai, Kanoko Kohmura, Yoshito Ueyama, Mamoru Ito, Yasuo Ikeda, Masahiro Kizaki, Masato Nakamura BBRC, 313:258-262,2004

3.Prompt Tumor Formation and Maintenance of Constitutive NF-κB activity of Multiple Myeloma Cells in NOD/SCID/γcnull Mice
Md.Zahidunnabi Dewan, Mariko Watanabe, Kazuo Terashima, Mizuho Aoki, Tetsutaro Sata, Mitsuo Honda, Mamoru Ito, Shoji Yamaoka, Toshiki Watanabe, Ryouichi Horie, Naoki Yamamoto Cancer Sci., 95(7):564-568,2004

4.Development of both Human Connective Tissue-type and Mucosal-type mast Cells in Mice from Hematopoietic Stem Cells with Identical Distribution Pattern to Human Body
Naotomo Kambe, Hidefumi Hiramatsu, Mika shimonaka, Hisanori Fujino, Ryuta Nishikomori, Toshio Heike, Mamoru Ito, Kimio Kobayashi, Yoshito Ueyama, Norihisa Matsuyoshi, Yoshiki Miyachi, Tatsutoshi Nakahata Blood, 103(3):860-867,2004

5.Retinoic acid syndrome in NOD/scid mice induced by injecting an acute promyelocytic leukemia cell line
Ninomiya, M., H. Kiyoi, M. Ito, Y. Hirose, and T. Naoe Leukemia., 18:442-448., 2004

6.Development of multiple immunodeficient NOD/SCID/γc null (NOG) mice and their application on in vivo experimental medicine.
Ito M J. Germfree Life Gnotobiol., 34:18-21., 2004

7.「免疫不全NOGマウスを用いたヒト巨核球・血小板造血の解析 」
宮川義隆、中村隆典、吉田寛、伊藤守 Molecular Medicine, 41(12),2004

2003年


1.Complete Reconstitution of Human Lymphocytes from Cord Blood CD34+ Cells Using the NOD/SCID/γcnull Mice Model
Hidefumi Hiramatsu, Ryuta Nishikomori, Toshio Heike, Mamoru Ito, Kimio Kobayashi, Kenji Katamura, Tatsutoshi Nakahata Blood, 102:873-880,2003

2.Functional CD5+ B Cells Develop Predominantly in the spleen of NOD/SCID/γcnull (NOG) Mice Transplanted either with Human Umbilical Cord Blood, Bone Marrow and Mobilized Peripheral Blood
CD34+ Cells Takuya Matsumura, Yoshie Kametani, Kiyoshi Ando, Yasuyuki Hirano, Ikumi Katano, Ryoji Ito, Masashi Shiina, Hideo Tsukamoto, Yuki Saito, Yutaka Tokuda, Shunichi Kato, Mamoru Ito, Kazuo Motoyoshi, Sonoko Habu Exp. Hematol. 31:789-797,2003

3.Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γcnull Mice: Suppression by an Inhibitor against NF-κB
M.Zahidunnabi Dewan, Kazuo Terashima, Midori Taruishi, Hideki Hasegawa, Mamoru Ito, Yuetsu Tanaka, Naoki Mori, Tetsutaro Sata, Yoshio Koyanagi, Michiyuki Maeda, Yoko Kubuki, Akihiko Okayama, Masahiro Fujii, Naoki Yamamoto J. Virology, 77(9):5286-5294,2003

4.「異種動物を用いたヒト造血幹細胞の測定」
平松英文、中畑龍俊 ファルマシア,39(2):118-122,2003

5.NOG (NOD/Shi-scid, γcnull) mouse-HIV-1 and HTLV-1infection model using NOG mice allowing an efficient transplantation of human cells
Ito M, Koyanagi Y, Terashima K, Yamamoto N, Nakahata T, Ueyama Y, Tamaoki N, Nomura T Proc. Japanese Society of Aminal Models for Human Diseases, 19:23-30.,2003

2002年


1.NOD/SCID/γcnull Mouse: an Excellent Recipient Mouse Model for Engraftment Human Cells
Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi, Kazutomo Suzue, Mariko Kawahata, Kyoji Hioki, Yoshito Ueyama, Yoshio Koyanagi, Kazuo Zugamura, Kohichiro Tsuji, Toshio Heike, Tatsutoshi Nakahata Blood, 100(9):3175-3182,2002

2.The in vivo Development of Human T Cells from CD34+ Cells in the Murine Thymic Environment
Yuki Saito, Yoshie Kametani, Katsuto Hozumi, Naoko Mochida, Kiyoshi Ando, Mamoru Ito, Tatsuji Nomura, Yataka Tokuda, Hiroyasu Makuuchi, Tomoo Tajima, Sonoko Habu Int. Immunology, 14(10):1113-1124,2002

3.Functional Human T Lymphocyte Development from Cord Blood CD34+ Cells in Nonobese Diabetic/Shi-scid, IL-2 Receptor γ Null Mice
Takashi Yahata, Kiyoshi Ando, Yoshihiko Nakamura, Yoshito Ueyama, Kazuo Shimamura, Norikazu Tamaoki, Shunichi Kato, Tomomitsu Hotta J. Immunology, 169:204-209,2002

4.「NOD/SCID/γc-/-マウスを用いたヒト造血幹細胞の解析」
平松英文、中畑龍俊 Annual Review 血液,2002

2001年


1.「ヒューマウスの進歩」
上山義人、伊藤守 組織培養工学,27(7),2001

2.「NOD/SCIDマウスにおけるヒト造血と免疫の再構築」
平松英文、中畑龍俊 分子細胞治療, 2(5),2001

3.「HIVモデル動物」
伊藤守 総合臨床, 50(10):2693-2695,2001